Since you can't use the remote, have you tried pulling the plug for a minute or so then plugging back in to restart? This may trigger a restart if the pairing routine.
If the remote still doesn't work, if you have an Android or iOS mobile device you may be able to control the Roku via the Roku mobile app.
Roku Community Streaming Expert
I am not a Roku employee, only a user like you. Please, no support questions via private message -- post them publicly to the Community where others may benefit as well.
If this post solves your problem please help others find this answer by clicking "Accept as Solution.".
Ultra 4800 | Streaming Stick 4K+ 3821 | TCL Roku TV 43S245/C107X