Are you saying the Roku device is currently in Guest mode? If so, you disable it by logging into your Roku user account on their web site (https://my.roku.com), find the device in the list, click on the device and turn Guest mode off.
If you're not in Guest mode, there should not be any prompt to enter guest mode when you boot or use the Roku. You have to dig into the menus to enable it, and then once it's enabled you can't disable it from the device.
If you're asking if that menu option can be hidden or removed, the answer is no.
Dan
Roku Community Streaming Expert
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