@Videohooligan, the channels are tied to the account, not the device, so your channels should remain with the account. However, I don't know what happens if there's no longer a device associated with the account. I think the account remains intact ready to be linked to a device, but I've never tested it. You also may have to log into some services when you factory reset to switch from one account to another and back.
Traveling with Roku devices to different regions can be problematic. As you've seen, you only get access to the channels for the region of the account. Moving the device to a different region doesn't change the region associated with the account. There's also Geo-restrictions that many providers put in place, so if you took a device associated with a UK account to the US, the UK channels would still be there, but they would be blocked by the provider. I've also seen problems where people purchased a US device and it didn't work properly in the UK. It appears some of those UK providers take the model number into consideration when allowing access or for some reason the US models are flagged as incompatible.
To be honest, if I were traveling often I'd get two devices and have one associated with a UK account and the other with a US account. I believe they're cheaper here, so you might want to pick up a device the next time you're here just for use in the US.
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