Try disconnecting the power from the Roku device for a few seconds and plug it back in while the light on the remote is flashing. Make sure you have good, fresh batteries and you're holding it close to the Roku.
Roku Community Streaming Expert
Help others find this answer and click "Accept as Solution." If you appreciate my answer, maybe give me a Kudo.
Thank so much for your response. However, that did not solve the issue. The ROKU words scroll up and down my screen but the remote is ineffective. The green lite does show it has power and the batteries are new. THIS IS FRUSTRATING. There is no menu or settings screen.