We have the same experience with the remote gone crazy. It's making us crazy. The Roku 1 and 3 never had this problem.
I have the same issue with my Ultra remote. When I hit the arrow keys or when I press FF, it kicks me out of whatever app I am in and wants to open Hulu!!! I don't even have a Hulu subscription. Something in the remote buttons is clearly crossed-up randomly. And no, I'm not hitting the "Hulu" button my accident, before anyone says that. This is only happening with my Ultra remote. I also have a Roku TV and a Roku Stick on my garage set and those remotes never do this.