If this is a point-anywhere remote that controls the Roku via wifi-direct (as opposed to a direct line of site remote that controls via infrared) I've seen some indication that this can be caused by your router using a channel that is crowded with a bunch of nearby routers using the same channel. Your remote has to work too hard constantly sorting through the information packets from all those other remotes and it uses up the batteries much too quickly.
If you know how to access your router's setup, see if setting your router to use a different channel helps. In the 2.4 GHz wifi band, channels 1, 6, and 11 often give the best performance as they do not overlap each other. It can also help to set the router to use 20 kHz bandwidth instead of 40, to minimize interference from adjacent channels.
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Streaming Stick 4K+ 3821 | Streaming Stick+ 3810 | TCL Roku TV 43S245/C107X
