I have a 55" TCL Roku TV (55S405). When I play an MKV file with 2 channel AAC audio, every 10 seconds or so the audio drops out for a fraction of a second. It makes the content completely unwatchable. This only started happening after my TV updated to 10.0.0 (build 4195-3.0) a few days ago.
It doesn't matter if I play audio through my HDMI ARC sound bar or if I disconnect the sound bar and use the TV speakers. The behavior is the same.
Looking at Plex forums and Reddit, it looks like many people are experiencing the same issue.