Vad
Similar behavior in this other posting. https://community.roku.com/t5/Channels-viewing/home-page-channel-icons-disappearing/m-p/910610#M150266
Seems like a recent development. Used to occur occasionally on some devices when in Guest Mode, but haven't heard about it much when not in Guest Mode, other than isolated cases. (also, this was fixed via a build update to the OS). Generally, a reboot of the Roku device fixed the Home Screen issues, but not seem to be working with this newest development.
Don't bother with a Factory Reset. Does not seem to fix the issue.
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Perhaps RokuJohnB or other moderator can gather some info and forward to appropriate team to look into.