While it's an old thread, Plex on Roku still has not fixed this issue.
I quit using PLEX as it has tooooooo many problems. Used it for years, but the developers are constantly breaking things or refuse to fix items or take years to address issues. The Emby player on Roku has NEVER failed to work for me, and plays EAC 5.x just fine on Ruko without having to go reconfigure it like when running Plex. I just set audio for Auto and Emby always works.
Do yourself a favor and leave Plex and move over to the Emby solution. I run both on TrueNAS still, but rarely use Plex except as a music server hosts for Alexa...